Project summaries

This is a collection of automatically generated descriptions for projects in the Open Source Brain Repository.
SolinasEtAl-GolgiCell Multicompartmental model of cerebellar Golgi cell from: Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D'Angelo E. (2007) Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar Golgi cells.
GranCellSolinasEtAl10 Cerebellar granule cell model from Solinas S, Nieus T and D`Angelo E (2010) A realistic large-scale model of the cerebellum granular layer predicts circuit spatio-temporal filtering properties. Front. Cell. Neurosci.
GranuleCell A project illustrating the behaviour of the Granule Cell model from: Maex, R and De Schutter, E. Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the Cerebellar Granule Cell Layer J Neurophysiol, Nov 1998; 80: 2521 - 2537. Based on scripts obtained from: http://www.tnb.ua.ac.be/models/network.shtml.
GranuleCellVSCS Conversion to NeuroML of a model granule cell developed by Volker Steuber and Chiara Saviane.
CerebellarNucleusNeuron Initial implememtation of Steuber, Schultheiss, Silver, De Schutter & Jaeger's 2011 Deep Cerebellar Nucleus cell model in NeuroML based on original GENESIS scripts.
PurkinjeCell An initial implementation in NeuroML of the Purkinje Cell model from De Schutter, E. and Bower, J. M. (1994). Based on Arnd Roth el al's conversion of the original GENESIS code to NEURON.
GranCellLayer An extension in 3D of the Granule Cell Layer model from: Maex, R and De Schutter, E. Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the Cerebellar Granule Cell Layer J Neurophysiol, Nov 1998; 80: 2521 - 2537.
VervaekeEtAl-GolgiCellNetwork Network of electrically coupled cerebellar Golgi cells, as described in Vervaeke et al. Rapid Desynchronization of an Electrically Coupled Interneuron Network with Sparse Excitatory Synaptic Input, Neuron 2010. The Golgi cell model is based on the abstract cell model in Solinas et al., Frontiers in Neuroscience 2007.
L5bPyrCellHayEtAl2011 Layer 5b Pyramidal cell constrained by experimental data on perisomatic firing properties as well as dendritic activity during backpropagation of the action potential.
MainenEtAl_PyramidalCell Implementation of the Mainen et al. pyramidal cell model from: Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995) A model of spike initiation in neocortical pyramidal neurons. Neuron 15:1427-39. This project is based on scripts obtained from: http://senselab.med.yale.edu/senselab/modeldb/ShowModel.asp?model=8210.
RothmanEtAl_KoleEtAl_PyrCell A project which was used in Rothman et al. "Synaptic depression enables neuronal gain control" Nature 2009 to demonstrate gain control in realistic cell models. Based on cell model from Kole et al. 2008 (obtained from http://senselab.med.yale.edu/modeldb/ShowModel.asp?model=114394).
CA1PyramidalCell Conversion of CA1 cell from Migliore et al 2005: http://senselab.med.yale.edu/ModelDB/ShowModel.asp?model=55035. This model can currently be executed in NEURON, GENESIS, MOOSE and PSICS.
CElegans This is a neuroConstruct project incorporating reconstructed CElegans cells (originally in Blender format).