Explore Open Source Brain

These are just a selection of some stable, well-tested projects on OSB. To see all projects click here.

Neocortex

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Hay et al. 2011

Layer 5b pyramidal cell constrained by experimental data on perisomatic firing properties as well as dendritic activity during backpropagation of the action potential.

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Smith et al. 2013

Multicompartmental model of Layer 2/3 pyramidal cell used for investigating dendritic spiking

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Allen Institute Cell Types DB

Conversion of cell models and data to NeuroML from Allen CellTypes Database

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Markram et al. 2015

A project to illustrate how models and data from the Blue Brain Project can be converted to NeuroML and PyNN

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Pospischil et al. 2008

Minimal Hodgkin-Huxley type models for different classes of cortical and thalamic neurons

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Sadeh et al. 2017

Models of Inhibition Stabilized Networks in mammalian neocortex

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Multiscale ISN

Inhibition Stabilized Network featuring point neurons providing input to detailed L2/3 pyramidal cells

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Traub et al. 2005

Single-column thalamocortical network model with 14 multicompartmental cell populations

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Potjans & Diesmann 2014

Microcircuit model of early sensory cortex displaying asynchronous irregular activity with layer-specific firing rates

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Brunel 2000

Sparsely connected spiking neuron network from Brunel 2000

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Izhikevich spiking neuron model

Spiking neuron model originally described in Izhikevich 2003, which can reproduce a range of firing behaviors

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M1 Network model

A multiscale model of mouse primary motor cortex (M1).

Cerebellum

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Maex and De Schutter 1998

Granule Cell Layer network model with single compartment, conductance based cells

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Vervaeke et al. 2010

A network model of electrically coupled cerebellar Golgi cells, as described in Vervaeke et al. 2010

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Solinas et al. 2007

Multicompartmental cerebellar Golgi cell model demonstrating ionic currents underlying pacemaking and electroresponsiveness of these cells

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Cayco-Gajic, Clopath, Silver 2017

Model of cerebellar granule cell layer used to investigate how sparse synaptic connectivity influences pattern separation.

Hippocampus

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Migliore et al. 2005

Morphologically detailed model of CA1 Pyramidal cell

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Wang & Buzsáki 1996

Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model

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Ferguson el al. 2013

A two-variable simple model derived from patch-clamp recordings from the CA1 region of a whole hippocampus preparation of PV+ fast-firing cells

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Pinsky and Rinzel 1994

A 2-compartment (soma and dendrite), conductance-based (Hodgin-Huxley type) model of a hippocampal CA3 pyramidal neuron

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Bezaire el al. 2016

A large-scale, detailed, biologically constrained network model of the rodent hippocampal CA1 area

Olfactory bulb

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Migliore et al. 2014

Migliore et al. (2014) 3D Model of the Olfactory Bulb

Invertebrate models

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Hodgkin and Huxley 1952

A tutorial designed to give an overview of the Hodgkin-Huxley model

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Boyle & Cohen 2008

A NeuroML 2 implementation of the C. elegans muscle cell model of Boyle & Cohen 2008, as used in the OpenWorm project.

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Prinz et al. 2004

Implementation of the pyloric network of the lobster stomatogastric ganglion system of Prinz, Marder, et al.

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Fitzhugh Nagumo model

The Fitzhugh Nagumo model is a two-dimensional simplification of the Hodgkin-Huxley model of spike generation in squid giant axons.

Neuronal reconstructions

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NeuroMorpho.Org

Set of example reconstructed neuronal morphologies taken from NeuroMorpho.Org in NeuroML format.

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Janelia MouseLight

Showcase project on OSB for neuronal reconstructions from the Janelia MouseLight project.



Please be patient, the information is being retrieved from the OSB database.



Please be patient, the information is being retrieved from the OSB database.



Please be patient, the information is being retrieved from the OSB database.



Please be patient, the information is being retrieved from the OSB database.



Please be patient, the information is being retrieved from the OSB database.



Please be patient, the information is being retrieved from the OSB database.



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