Large-scale network model of a neocortical slice exhibiting persistent gamma oscillations, written for the VERTEX simulator (a Matlab simulator for modelling spatially realistic LFPs from spiking neural networks containing simplified compartmental neuron models). The model contains ~175 000 neurons arranged into 4 layers (layer 1 is empty, layers 2/3 combined). Anatomy is based on the connectivity data in Binzegger et al. 2004. Neuron firing dynamics are based on the dynamics of the neurons described in Traub et al. 2005, implemented as AdEx neurons with a small number of passive dendritic compartments. The model size is approximately the same size as a comparison experimental cortical slice. The simulation also includes a virtual Utah array, so calculates LFPs at 100 locations across the space of the model. Comparison experimental data is available on figshare:

Not yet started conversion to NeuroML 2

NeuroML v2.x support

NEURON support

Developer: Rokas Stanislovas
Scientific Coordinator: Richard Tomsett

The original published version of this model is available on ModelDB

This model was originally developed in: MATLAB

The code for this model is hosted on GitHub:

Tags: Large scale network simulationLocal Field PotentialsAdaptive exponential integrate and fire neuronInterneuron